Mcc & CarboxymethylCellulose Sodium IP/USP
Miccel – CMC
Solution for Suspensions, Lotions and Creams
Suspension
As suspending agent for readily constitutable suspension Absence of sedimentation in some of formulation.
Lotion
As oil/water emulsifier for lotions and creams
Creams
Emulsion Stabilizer and thickener with opacifier for creams and gels.
MICCEL CMC is the mixture of microcrystalline cellulose and carboxymethyl cellulose Sodium various ratio depend on application.
| Sr.no | Test | Specification |
|---|---|---|
| 1 | Description | Tasteless, odoriess, white, coarse to fine powder. |
| Solubility | Swells in water, producing, when dispersed, a white, opaque dis or gel Insoluble in organic solvents and in dilute acids. | |
| 2 | Identification | |
| Test-A | A white opaque, dispersion is produced that does not settle on Standing. | |
| Test-B | Each drop forms a white, opaque globule that does not disperse standing | |
| Test-C | No blue or purplish blue color produced. | |
| 3 | Assay, % CMC sodium | Refer chart |
| 4 | Impurities | |
| Residue on ignition% | NMT 5.0 | |
| Heavy Metals, pg/g | NMT 10 | |
| 5 | Specific Test | |
| Viscosity-Rotational Method, % of that stated on the label, In Cps | ||
| pH | 60.0-140.0 | |
| Loss on drying, % | NMT 8.0 |
Grade Wise in House Specification
| Test | MICCEL CMC – 501 | MICCEL CMC – 581 | MICCEL CMC – 591 | – 591 MICCEL CMC – 611 |
|---|---|---|---|---|
| Viscosity ,cps(by Labman Viscometer, Model – LMDV 200L, Spindle no. 2) | Between 70 and 170 (2.1 % Solid) | Between 70 and 170(2.1% Solid) | Between 40 and 95 (1.2 % Solid) | Between 50 and120 (2.6% Solid) |
| Assay, % (NLT 75% and NMT 125% of the labeled amount of Carboxymethylcellulose Sodium, Calculated on dried basis) | 7.1 to 11.9 | 8.3 to 13.8 | 8.3 to 13.8 | 11.3 to 18.8 |
| Retention on 60 # (%) | NMT 0.1 | NMT 0.1 | NMT 0.1 | NMT 0.1 |
| Retention on 200 # (%) | NMT 40 | NMT 35 | ||
| Retention on 325 # (%) | NMT 45 | NMT 50 |
Packaging Details
Available Packaging Type:
HDPE/Paper bags – 25Kg
Fiberboard/HDPE – 25Kg
*Our standard packaging in 25 Kg bags. We can also customize packaging as per customers request at additional cost
Container
20 Ft. (Approx Wt.)
40 Ft. (Approx Wt.)
Palletized
10,000 Kg
20,000 Kg
Non-Palletized
11,000 Kg
25,000 Kg
Packaging Details
Available Packaging Type:
1. HDPE/Paper bags – 25Kg
1. Fiberboard/HDPE – 25Kg
*Our standard packaging in 25 Kg bags. We can also customize packaging as per customers request at additional cost
Container
20 Ft. (Approx Wt.)
40 Ft. (Approx Wt.)
Palletized
10,000 Kg
20,000 Kg
Non-Palletized
11,000 Kg
25,000 Kg
Unique Features of Microcrystalline Cellulose & Carboxymethyl Cellulose Sodium IP/USP
Angle of Repose
Customized Bulk Density
Excellent Flowability
Better Compressibility
Frequently Asked Questions
How is the combination of Microcrystalline Cellulose (MCC) and Carboxymethyl Cellulose Sodium (CMC) IP/USP commonly used in pharmaceutical formulations?
Blend of MCC and CMC is commonly used in pharmaceutical formulations as suspensions, lotions and creams as emulsifier or thickener in gels.
How do MCC & Carboxymethyl Cellulose Sodium IP/USP blends contribute to formulation stability and shelf life?
It contributes to formulation stability by its suspension and emulsifying propertyies and has shelf life of 5 years from manufacturing date.
Can Ankit Pulps and Boards create custom MCC & CMC blends for unique formulation needs?
Yes, our proficient technical team is capable of meeting your customization needs.
How do MCC & Carboxymethyl Cellulose Sodium IP/USP blends improve the patient experience with orally disintegrating tablets (ODTs)?
The MCC and CMC blends improve the patient experience by formulating oral disintegrating tablets which disintegrates rapidly.
Can you explain how Ankit Pulps and Boards ensures the quality of its MCC & CMC blends for IP/USP compliance?
Ankit Pulps and Boards ensure our quality as we are having entirely automated facility, thereby adhering finished product quality.